📋 Indications & Clinical Dosage
*Active immunization against diphtheria, tetanus, pertussis, Hepatitis B and Haemophilus influenzae type B:*
BY DEEP SC OR IM INJ: Children 2 month-4 yr: 3 separate injections each of 0.5 ml at interval of minimum of 4 weeks; not recommended above 4 years age.
⛔ Contraindications
Severe local or general reaction to a preceding dose, neurological disease, acute illness, history of convulsions, cerebral irritation or damage in the neonatal period.
⚠️ Precautions & Warnings
History of familial epilepsy. Children with history of severe local reaction to a preceding dose should be given DPT in one limb and Hib in another.
⚠️ Adverse Reactions / Side Effects
Fever, irritability, persistent crying, headache loss of appetite; malaise, somnolence, allergy, local pain, neurological effects.
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.