📋 Indications & Clinical Dosage
*Active immunization against hepatitis A:*
BY IM INJ: Adults & above 16 yr: Primary immunization: 1 ml (1440 ELISA units) into deltoid muscle; Booster: 1 ml (1440 ELISA units) 6-12 monthafter primary dose. It is unnecessary to repeat the primary vaccination schedule if a booster is given within 5 yr of primary vaccination.
Children 1-15yr: Primary immunization: 0.5 ml (720 ELISA units), into deltoid muscle. Booster: 0.5 ml(720 ELISA units) 6-12 monthafter primary dose.
⛔ Contraindications
Severe febrile infections.
⚠️ Precautions & Warnings
Pregnancy, lactation. Infection, haemo dialysis, altered immunity.
⚠️ Adverse Reactions / Side Effects
Fever, malaise, fatigue, nausea, loss of appetite, mild transient soreness, erythema and irritation at injection site.
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.