👨‍⚕️ Clinically Reviewed by: PakistaniBano Medical Editorial Board (Pharm.D Panel)
📅 Reviewed: November 2026 • 🔍 Authority: DRAP / WHO ATC
📦 Formulations, Pack Sizes & Retail Prices Currency: Rs.
Dosage Form Reg. No Pack Size Trade Price (TP) Maximum Retail Price (MRP)
Cap 400 mg 022416 5 Rs.459 —
Susp100 mg 022415 30 ml Rs.259 Rs.305
Susp100 mg 022415 60 ml Rs.320 Rs.377
Susp DS 200 mg 044340 30 ml Rs.314 Rs.370
Tab 200 mg 070790 10 Rs.475 Rs.559

📋 Indications & Clinical Dosage

*Acute infections due to sensitive Gram-positive and Gram-negative bacteria, Upper & Lower Respiratory Infection, Urinary Tract Infection:* Adult: 200-400 mg daily in 1-2 divided doses. Children 6-11 months: 75 mg daily; 1-4 years: 100 mg daily; 5-9 years: 200 mg daily; 10-17 years: 200-400 mg daily, alternatively100-200 mg twice daily Uncomplicated gonorrhea, Otitis Media: Adults & Children 12 yrs: 400 mg once daily or 200 mg every 12 hr; 6 months- 12 yrs: 8 mg/ kg once daily or 4 mg/kg every 12 hr.

⚠️ Precautions & Warnings

Severe hepatic and renal impairment, hypersensitivity to B-lactams.

🔄 Drug Interactions

Anticoagulants, probenecid, carbamazepine.

⚠️ Adverse Reactions / Side Effects

Abdominal discomfort, agranulocytosis,allergic reactions,anaphylaxis, aplastic anaemia, blood disorders, confusion, disturbances in liver enzymes, dizziness, eosinophilia, haemolytic anaemia, hallucinations, headache, hypertonia, leucopenia, nervousness, pruritus, rashes, fever and arthralgia, sleep disturbances, urticaria, GI disturbances, Rare: Stevens-Johnson syndrome, thrombocytopenia, toxic epidermal necrolysis, transient cholestatic jaundice, transient hepatitis

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:
No evidence of risk Inj humans.
Lactation / Breastfeeding:
Caution advised or effect undetermined.

📚 Official Regulatory & Clinical References

  • Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
  • World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
  • Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.

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