👨‍⚕️ Clinically Reviewed by: PakistaniBano Medical Editorial Board (Pharm.D Panel)
📅 Reviewed: November 2026 • 🔍 Authority: DRAP / WHO ATC
📦 Formulations, Pack Sizes & Retail Prices Currency: Rs.
Dosage Form Reg. No Pack Size Trade Price (TP) Maximum Retail Price (MRP)
Cap 500 mg — 12 Rs.153.00 Rs.180.00

📋 Indications & Clinical Dosage

*Susceptible infections due to sensitive Gram-positive and Gram-negative bacteria:* Adult: 0.5-1 g twice daily; Children 6-17 years (body-weight up to 40 kg): 0.5 g twice daily. Children 6-17 years (body-weight 40 kg and above): 0.5-1 g twice daily. *Skin infections, Soft-tissue infections, Uncomplicated urinary-tract infections:* Adult: 1 g daily; Children 6-17 years (body-weight 40 kg and above): 1 g once daily. Dose to be taken for 10 days.

⚠️ Precautions & Warnings

Renal and hepatic impairment, hypersensitivity

🔄 Drug Interactions

Anticoagulants. Loop diuretics

⚠️ Adverse Reactions / Side Effects

Abdominal discomfort, agranulocytosis, allergic reactions, anaphylaxis, aplastic anaemia, blood disorders, confusion, disturbances in liver enzymes, dizziness, eosinophilia, haemolytic anaemia, hallucinations, headache, hypertonia, leucopenia, nervousness, pruritus, rashes, fever and arthralgia, sleep disturbances, urticaria, GI disturbances, Rare: Stevens-Johnson syndrome, thrombocytopenia, toxic epidermal necrolysis, transient cholestatic jaundice, transient hepatitis,

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:
No evidence of harm
Lactation / Breastfeeding:
Caution advised

📚 Official Regulatory & Clinical References

  • Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
  • World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
  • Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.

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