ABENIX (ABEMACICLIB) Price

Dosage Form	Reg. No	Pack Size	Trade Price (TP)	Maximum Retail Price (MRP)
Tab 150 mg	—	—	—	—

📋 Indications & Clinical Dosage

*Breast cancer (specialist use only):* Adult: 150 mg twice daily, for dose adjustments, treatment interruption, or discontinuation due to side-effects consult product literature.

⚠️ Precautions & Warnings

Severe hepatic and renal impairment. Monitor full blood count, and alanine and aspartate aminotransferases before starting treatment, every 2 weeks for the first 2 months, monthly for the following 2 months thereafter. Use effective contraception in women of childbearing potential during treatment and for at least 3 weeks after completing treatment.

🔄 Drug Interactions

CYP3A4 inhibitor

⚠️ Adverse Reactions / Side Effects

Alopecia, anaemia, appetite decreased, decreased leucocytes, diarrhoea, dizziness, dyspepsia, embolism and thrombosis, excessive tearing, fatigue, fever, headache, increased risk of infection, muscle weakness, nail disorder, nausea, neutropenia, respiratory disorders, skin reactions, stomatitis, taste altered, thrombocytopenia, vomiting. Rare: Neutropenic sepsis

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:

Avoid unless essential

Lactation / Breastfeeding:

Contraindicated. Discontinue breast feeding

📚 Official Regulatory & Clinical References

Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.