📋 Indications & Clinical Dosage
*Seasonal allergic rhinitis, perennial rhinitis:*
Adults & Children 12 yrs: 2 sprays in each nostril once daily in the morning; maintenance: 1 spray in each nostril once daily, use minimum effective dose. Max 4 sprays in each nostril daily. Children 4-11 yrs: 1 spray in each nostril once daily in the morning; max 2 sprays in each nostril daily.
⚠️ Precautions & Warnings
Avoid in pulmonary tuberculosis, avoid after nasal surgery (until healed), avoid in the presence of untreated nasal infections (treat infection first), patients transferred from systemic corticosteroids may experience exacerbation of some symptoms, caution in conditions of stress, trauma, surgery, infection, pregnancy and lactation. Monitor patients for signs of adrenal insufficiency, monitor growth in adolescents in prolong therapy
🔄 Drug Interactions
Potent inhibitors of CYP3A4.
⚠️ Adverse Reactions / Side Effects
Aggression and anxiety (in children), headache, dryness, epistaxis, hypersensitivity reactions, nasal and throat irritation, nasal ulceration, sleep disturbances, smell disturbances, taste disturbances. Rare: Bronchospasm, anaphylaxis
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.