APSIN (FAMOTIDINE) Price

Dosage Form	Reg. No	Pack Size	Trade Price (TP)	Maximum Retail Price (MRP)
Syp 40 mg/5 ml	052957	120 ml	Rs.212.50	Rs.250.00
Tab 20 mg	046460	2x10	—	Rs.236.04 277.69
Tab 40 mg	046461	10	—	Rs.229.50 270.00

📋 Indications & Clinical Dosage

*Treatment of benign gastric and duodenal ulceration:* Adult: 40 mg once daily for 4-8 weeks, dose to be taken at night. *Prophylaxis of duodenal ulcer relapse:* Adult: 20 mg once daily, dose to be taken at night. *Zollinger-ellison syndrome:* Initially 20 mg every 6 hr, adjust as necessary; max 800 mg daily. *Reflux oesophagitis:* Adult: 20-40 mg twice daily for 6-12 weeks; maintenance 20 mg twice daily

⛔ Contraindications

Hypersensitivity, gastric malignancy.

⚠️ Precautions & Warnings

Gastric carcinoma Impaired, renal impairment, liver impairment.

⚠️ Adverse Reactions / Side Effects

Blood dyscrasias, hypotension, tachycardia, emesis, headache, dizziness, constipation, diarrhoea, nausea, dry mouth, bradycardia, anorexia, cholestatic jaundice, anaphylaxis, angioedema, arthralgia, muscle cramp,renal failure, abnormal liver enzymes, CNS disturbances. Rarely reversible gynaecomastia, toxic epidermalnecrolysis, chest tightness, interstitial pneumonia, paraesthesia, seizures

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:

Avoid unless potential benefit outweighs risk.

Lactation / Breastfeeding:

Not recommended.

📚 Official Regulatory & Clinical References

Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.