📋 Indications & Clinical Dosage
*Benign Prostatic Hyperplasia (BPH):*
Adult: 8 mg once daily, reduce dose to 4 mg once daily in patients with renal impairment.
⛔ Contraindications
Severe hepatic impairment, severe renal impairment, concomitant use of CYP3A4
⚠️ Precautions & Warnings
Diabetes mellitus, mild to moderate hepatic or renal impairment, hypotension
🔄 Drug Interactions
Antivirals and Antifungals (azole family), CYP3A4
⚠️ Adverse Reactions / Side Effects
Diarrhoea, headache, dizziness, allergic reactions, retrograde ejaculation, hypotention, nasopharyngitis, nasal congestion
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.