📋 Indications & Clinical Dosage
*Symptomatic benign prostatic hyperplasia (BPH):*
Adults (male): 500 mcg daily, review treatment at 3-6 months and then every 6-12 months (may require several months treatment before benefit is obtained).
Children: Not recommended.
⛔ Contraindications
Severe hepatic impairment, women, children, adolescents.
⚠️ Precautions & Warnings
Mild to moderate hepatic impairment. Avoid donating blood until minimum 6 months after last dose.
🔄 Drug Interactions
Verapamil, diltiazem
⚠️ Adverse Reactions / Side Effects
Impotence, decreased libido, ejaculation disorders, gynaecomastia, breast tenderness and enlargement
🤰 Pregnancy & Lactation Safety
Pregnancy Risk:
Contraindicated in pregnancy.
Lactation / Breastfeeding:
Contraindicated, avoid
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.