📋 Indications & Clinical Dosage
*Bronchospasm with reversible obstructive airway disease:*
Adults & Children above 12 years: 0.63mg-1.25mg every 8 hours as needed
Children upto 4 yrs: 0.31 mg-1.25 mg every 4-6 hours as needed, Children 5-11 yrs: 0.31 mg-0.63 mg every 8 hours as needed.
*Exacerbations of Asthma:*
Adults & Children above 12 years: 1.25 mg-2.5 mg every 20 minutes for 3 doses, then 1.25 mg-5 mg every 1-4 hours as needed.
Children: 0.075 mg/kg (min dose 1.25 mg) every 20 minutes for 3 doses, then 0.075 mg-015 mg, (max 5 mg) every 1-4 hours as needed.
⚠️ Precautions & Warnings
Severe cardiovascular disorders, severe liver cirrhosis, coronary insufficiency, hypertension and cardiac arrhythmia. In patients with convulsive disorders, hyperthyroidism, or diabetes mellitus and patients who are unusually responsive to sympathomimetic amines.
🔄 Drug Interactions
Beta-blockers, xanthine derivative,
mineral corticoids and diuretic, quinidine, disopyramide,
procainamide, phenothiazines, MAOIs,
tricyclic inhibitors, levodopa, I-thyroxine, oxytocin.
⚠️ Adverse Reactions / Side Effects
Allergic reaction, flu syndrome, body pain, back pain, tachycardia, migraine, dyspepsia, leg cramps, dizziness, hypertonia, tremor, cough, rhinitis, sinusitis, edema, nervousness
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.