📋 Indications & Clinical Dosage
*Chronic constipation:*
Adult & Children above 12 yr: 1-3 sachets daily in divided doses for up to 2 weeks; maintenance 1-2 sachets daily, dissolved in half a glass (approx125 ml) of water.
*Faecal impaction:*
Child above 12 yrs & adult: 4 sachets on first day, then increased in steps of 2 sachets daily, dose to be drunk within a 6 hour period, dissolved in half a glass (approx125 ml) of water, max. 8 sachets per day; after disimpaction, switch to maintenance laxative therapy if required.
⛔ Contraindications
Crohns disease, renal impairment, intestinal obstruction, intestinal perforation, paralytic ileus, severe inflammatory conditions of the intestinal tract, toxic megacolon, ulcerative colitis.
⚠️ Precautions & Warnings
Cardiovascular impairment discontinue if symptoms of fluidand electrolyte disturbance.
⚠️ Adverse Reactions / Side Effects
Abdominal distension and pain, nausea, flatulence.
🤰 Pregnancy & Lactation Safety
Pregnancy Risk:
Risk cannot be ruled out.
Lactation / Breastfeeding:
Caution advised or effect undetermined.
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.