Verified by DRAP 🩺 SOLUTIONS AFFECTING THE ELECTROLYTE BALANCE 🏷️ Electrolyte
👨‍⚕️ Clinically Reviewed by: PakistaniBano Medical Editorial Board (Pharm.D Panel)
📅 Reviewed: November 2026 • 🔍 Authority: DRAP / WHO ATC
📦 Formulations, Pack Sizes & Retail Prices Currency: Rs.
Dosage Form Reg. No Pack Size Trade Price (TP) Maximum Retail Price (MRP)
Inf — 1000 ml Rs.20.80 Rs.24.47
Inf — 500 ml Rs.16.10 Rs.18.94

📋 Indications & Clinical Dosage

*Replenishment of Extracellular Fluid (E.C.F.) to prevent reduced circulatory blood volume and interstitial fluid due to; trauma, scalds, burns and before, during and after surgery:* BY IV DRIP INF: Adults: Usual adult dosage is 500-1000 ml at one time by IV drip INF at the rate of 300- 500 ml per hr (about 75-125 drops per min).

⛔ Contraindications

Lactacidaemia (lactic acidosis) with severe liver damage.

⚠️ Precautions & Warnings

Cardiac failure reduced urinary output due to obstructive urinary tract diseases, hypertonic dehydration, renal failure, alkalosis, lactic acid metabolism disturbances. Sodium Chloride content of this solution is 6.0 gm/litre. Therefore, care should be taken in those cases where salt intake is restricted as in oedema, hypertension etc.

⚠️ Adverse Reactions / Side Effects

Cerebral, pulmonary and peripheral oedema and dilution acidosis may occur with a large volume and/or acute infusion.

📚 Official Regulatory & Clinical References

  • Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
  • World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
  • Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.
DRAP Registration Number: 015329

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