📋 Indications & Clinical Dosage
*Acne vulgaris:*
Adults: Apply sparingly once or twice daily for minimum 6-8 wk.
Children: Not recommended.
⛔ Contraindications
History or family history of cutaneous epithelioma, pregnancy (effective contraceptive measures must be taken 1 month before, during and 1 month after therapy) lactation
⚠️ Precautions & Warnings
Avoid eyes, mouth, and mucous membrane, abraded or sun-burnt skin, avoid UV light, lactation
🔄 Drug Interactions
Keratolytics.
⚠️ Adverse Reactions / Side Effects
Local irritation, dryness.
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.