📋 Indications & Clinical Dosage
*Symptomatic relief of seasonal allergic rhinitis:*
Adult & Children above 12 yrs: 180 mg once daily.
Children 6-11 yrs: 30 mg twice daily; 12-17 yrs: 120 mg once daily.
*Symptomatic relief of chronic idiopathic urticaria:*
Adult & Children above 12 yrs: 180 mg once daily.
⚠️ Precautions & Warnings
Caution in patients in narrow angle glaucoma, pyloroduodenal obstruction, urinary tract obstruction, urinary tract obstruction, hyperthyroidism, increased intraocular pressure, cardiovascular disease, severe renal impairment, epilepsy, prostatic hypertrophy
🔄 Drug Interactions
Aluminium and magnesium containing antacids.
⚠️ Adverse Reactions / Side Effects
Headache, drowsiness, dizziness, dry mouth, antimuscarinic effects, blurred vision, GI disturbances, psychomotor impairment
🤰 Pregnancy & Lactation Safety
Pregnancy Risk:
Contraindicated
Lactation / Breastfeeding:
Contraindicated
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.