📋 Indications & Clinical Dosage
*Chronic Strongyloides infection:*
Adult: 400 mg twice daily for 3 days, dose may berepeated after 3 weeks if necessary
Children 12-24 months: 200 mg as a single dose; Above 2 yr: 400 mg as a single dose.
*Hydatid disease, in conjunction with surgery to reduce the risk of recurrence or as primary treatment in inoperable cases:*
Adult: (consult product literature).
*Hookworm infections:*
Adult: 400 mg for 1 dose.
*E. granulosus, E. multilocularis:*
Adults: 800 mg daily in divided doses for 28 days followed by 14 albendazole-free days; up to 3 course of treatment may be given.
*Adjunct in surgical treatment, pre-operative:*
Adults: 800 mg daily in divided doses for 28 days followed by 14 albendazole-free days; repeat course once before surgery.
*Adjunct in surgical treatment, pre-operative & post-operative:*
Adults: 800 mg daily in divided doses for 28 days followed by 14 albendazole-free days; repeat cycle once.
⚠️ Precautions & Warnings
Perform blood counts and liver function tests before treatment and twice during each course of treatment,non-hormonal contraceptive measures must be taken during, and for one month after treatment.
🔄 Drug Interactions
Theophylline, anticonvulsants, oral contraceptives & hypoglycaemics, anticoagulants.
⚠️ Adverse Reactions / Side Effects
Anorexia, furred tongue, GI disturbances, nausea, headache, dizziness, rash, fever, reversible alopecia, haematological and liver enzyme changes.
🤰 Pregnancy & Lactation Safety
Pregnancy Risk:
Contraindicated
Lactation / Breastfeeding:
Contraindicated
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.