🩺 ANTIHISTAMINES FOR SYSTEMIC USE 🏷️ H1 receptor antagonist
👨‍⚕️ Clinically Reviewed by: PakistaniBano Medical Editorial Board (Pharm.D Panel)
📅 Reviewed: November 2026 • 🔍 Authority: DRAP / WHO ATC
📦 Formulations, Pack Sizes & Retail Prices Currency: Rs.
Dosage Form Reg. No Pack Size Trade Price (TP) Maximum Retail Price (MRP)
Tab 120 mg — 10 Rs.114.75 Rs.136.10
Tab 180 mg — 10 Rs.146.62 Rs.172.50
Tab 60 mg — 10 Rs.69.19 Rs.81.40

📋 Indications & Clinical Dosage

*Symptomatic relief of seasonal allergic rhinitis:* Adult & Children above 12 yrs: 180 mg once daily. Children 6-11 yrs: 30 mg twice daily; 12-17 yrs: 120 mg once daily. *Symptomatic relief of chronic idiopathic urticaria:* Adult & Children above 12 yrs: 180 mg once daily.

⚠️ Precautions & Warnings

Caution in patients in narrow angle glaucoma, pyloroduodenal obstruction, urinary tract obstruction, urinary tract obstruction, hyperthyroidism, increased intraocular pressure, cardiovascular disease, severe renal impairment, epilepsy, prostatic hypertrophy

🔄 Drug Interactions

Aluminium and magnesium containing antacids.

⚠️ Adverse Reactions / Side Effects

Headache, drowsiness, dizziness, dry mouth, antimuscarinic effects, blurred vision, GI disturbances, psychomotor impairment

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:
Contraindicated
Lactation / Breastfeeding:
Contraindicated

📚 Official Regulatory & Clinical References

  • Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
  • World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
  • Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.

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