🩺 DRUGS FOR CONSTIPATION 🏷️ Osmotic laxative
👨‍⚕️ Clinically Reviewed by: PakistaniBano Medical Editorial Board (Pharm.D Panel)
📅 Reviewed: November 2026 • 🔍 Authority: DRAP / WHO ATC
📦 Formulations, Pack Sizes & Retail Prices Currency: Rs.
Dosage Form Reg. No Pack Size Trade Price (TP) Maximum Retail Price (MRP)
Susp 3.35 gm/5 ml 041953 120 ml Rs.92.65 Rs.109.00

📋 Indications & Clinical Dosage

*Constipation:* Adult: Initially 15 ml twice daily, Children 1-11 months: 2.5 ml twice daily; 1-4 yrs: 2.5-10 ml twice daily; 5-17 yrs: 5-20 ml twice daily. Doses to be adjusted according to response. *Hepatic encephalopathy (portal systemic encephalopathy):* Adult: Adjusted according to response to 30-50 ml 3 times a day, subsequently adjusted to produce 2-3soft stools per day. Lactulose may take up to 48 hours to act.

⛔ Contraindications

Galactosaemia, intestinal obstruction.

⚠️ Precautions & Warnings

Lactose intolerance.

⚠️ Adverse Reactions / Side Effects

Hypokalemia, hyponatremia, dehydration, abdominal discomfort, cramps, flatulence, nausea, vomiting, diarrhea

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:
Caution advised
Lactation / Breastfeeding:
Caution advised

📚 Official Regulatory & Clinical References

  • Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
  • World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
  • Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.

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