📋 Indications & Clinical Dosage
*Symptomatic relief of gastro-intestinal disorders characterized by smooth muscle spasm, flatulence, abdominal discomfort and infant colic (Wind):*
Adults: 10 ml three to four times daily.
Children: 6 months-4 yrs: 5 ml before each feed, max four doses in 24 hr; 4-12 yrs: 5 to 10 ml four times daily.
⛔ Contraindications
Infants under 6 months.
⚠️ Precautions & Warnings
Patients with actual or suspected glaucoma or prostatic hypertrophy may exacerbate acid reflux in hiatus hernia, mental disturbance, mental depression, asthma, heart and kidney disease, infants and children.
🔄 Drug Interactions
Amantadine, atenolol, digoxin, pherthiazines, tricyclic antidepressants.
⚠️ Adverse Reactions / Side Effects
Weakness, drowsiness, nausea, thirst dry mouth, urinary retention, dizziness, exacerbation of glaucoma, CNS effects, photophobia, and xerostomia.
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.