CEFSPAN (CEFIXIME) Price

Dosage Form	Reg. No	Pack Size	Trade Price (TP)	Maximum Retail Price (MRP)
Cap 400 mg	013860	5	—	Rs.595.00 700.00
Susp 100 mg	010429	30 ml	—	Rs.337.45 397.00
Susp DS 200 mg	024634	30 ml	—	Rs.412.25 485.00

📋 Indications & Clinical Dosage

*Acute infections due to sensitive Gram-positive and Gram-negative bacteria, Upper & Lower Respiratory Infection, Urinary Tract Infection:* Adult: 200-400 mg daily in 1-2 divided doses. Children 6-11 months: 75 mg daily; 1-4 years: 100 mg daily; 5-9 years: 200 mg daily; 10-17 years: 200-400 mg daily, alternatively100-200 mg twice daily Uncomplicated gonorrhea, Otitis Media: Adults & Children 12 yrs: 400 mg once daily or 200 mg every 12 hr; 6 months- 12 yrs: 8 mg/ kg once daily or 4 mg/kg every 12 hr.

⚠️ Precautions & Warnings

Severe hepatic and renal impairment, hypersensitivity to B-lactams.

🔄 Drug Interactions

Anticoagulants, probenecid, carbamazepine.

⚠️ Adverse Reactions / Side Effects

Abdominal discomfort, agranulocytosis,allergic reactions,anaphylaxis, aplastic anaemia, blood disorders, confusion, disturbances in liver enzymes, dizziness, eosinophilia, haemolytic anaemia, hallucinations, headache, hypertonia, leucopenia, nervousness, pruritus, rashes, fever and arthralgia, sleep disturbances, urticaria, GI disturbances, Rare: Stevens-Johnson syndrome, thrombocytopenia, toxic epidermal necrolysis, transient cholestatic jaundice, transient hepatitis

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:

No evidence of risk Inj humans.

Lactation / Breastfeeding:

Caution advised or effect undetermined.

📚 Official Regulatory & Clinical References

Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.