📋 Indications & Clinical Dosage
*Urinary outflow obstruction and symptoms associated with benign prostatic hyperplasia:*
Adults: Initially 1 mg once daily, increasing if necessary after 1-2 week to 2 mg once daily, and then 4 mg once daily if required; max 8 mg daily for urinary outflow obstruction & symptoms associated with BPH.
*Hypertension:*
Adult: Initially 1 mg once daily, may be increased to double the dose every 1-2 week. Max: 8 mg/day.
Children: Not recommended.
⚠️ Precautions & Warnings
Care with initial dose (postural hypotension); monitor BP regularly, cataract surgery (risk of intra-operative floppy iris syndrome), elderly, heart failure, pulmonary oedema due to aortic or mitral stenosis, hepatic and renal impairment
🔄 Drug Interactions
Beta-blockers, diuretics, ACE inhibitors, calcium channel blockers, sildenafil, tadalafil, vardenafil.
⚠️ Adverse Reactions / Side Effects
Anxiety, back pain, coughing, dyspnea, fatigue, influenza-like symptoms, myalgia, paraesthesia, sleep disturbance, vertigo, agitation, angina, arthralgia, epistaxis, gout, hypoaesthesia, micturition disturbance, myocardial infarction, tinnitus, tremor, weight changes, angioedema, asthenia, blurred vision, depression, dizziness, drowsiness, dry mouth, erectile disorders, GI disturbances, headache, hypersensitivity, hypotension, intra-operative floppy iris syndrome, oedema, palpitations, postural hypotension, priapism, pruritus, rash, rhinitis, syncope, tachycardia