⛔ Contraindications
Severe psychosis, narrow angle glauco---_ma, history of malignant melanoma, history of neuroleptic malignant syndrome, history of non-traumatic rhabdomyolysis, phaeochromocytoma
⚠️ Precautions & Warnings
Hepatic and renal impairment, history of convulsions, history of myocardial infarction with residual arrhythmia, Cushings syndrome, diabetes mellitus, endocrine disorders, history of peptic ulcer ,hyperthyroidism, osteomalacia, phaeochromocytoma, psychiatric illness, severe cardiovascular disease, severe pulmonary disease, susceptibility to angle-closure glaucoma. Monitor blood values, hepatic, renal and cardiovascular function.
🔄 Drug Interactions
Drugs affecting central amines. MAOls, oral iron, drugs that cause hypotention, antihypertensives and sympathomimetics, ferrous sulphate.
⚠️ Adverse Reactions / Side Effects
Anorexia, anxiety, ataxia, arrhythmias, abnormal dreams, chorea, confusion, dementia, depression, dizziness, drowsiness, dry mouth, dyskinesia, dystonia, euphoria, fatigue, insomnia, nausea, palpitations, postural hypotension, psychosis, syncope, vomiting, chest pain, constipation, diarrhoea, dysphagia, flatulence, hand tremor, hoarseness, hypersalivation, hypertension, malaise, muscle cramps, oedema, reddish discoloration of the urine and other body fluids, weakness, weight changes, abdominal pain, hallucinations, insomnia. Rare: Myocardial infarction, ischaemic heart disease