📋 Indications & Clinical Dosage
*Parkinsons disease, used alone or as adjunct to cobeneldopaor co-careldopa for 'end-of-dose' fluctuations:*
Adult: 1 mg daily if used as monotherapy, 0.5 mg if used as adjunct; increased to 1 mg if needed.
🔄 Drug Interactions
Other MAOls, St. Johns Wort, pethidine, fluoxetine, fluvoxamine, dextromethorphan, sympathomimetic amines, antidepressants.
⚠️ Adverse Reactions / Side Effects
Anorexia, arthralgia, abnormal dreams, angina, conjunctivitis, constipation, depression, dry mouth, dyspepsia, flatulence, hallucinations, headache, influenza-like symptoms, leucopenia, rash, rhinitis, skin carcinoma, urinary urgency, vertigo, weight loss. Rare: Cerebrovascular accident, myocardial infarction