🩺 ANGIOTENSIN-II ANTAGONISTS, COMBINATIONS 🏷️ Angiotensin II antagonis/Calcium antagonist/Thiazide diuretic
👨‍⚕️ Clinically Reviewed by: PakistaniBano Medical Editorial Board (Pharm.D Panel)
📅 Reviewed: November 2026 • 🔍 Authority: DRAP / WHO ATC
📦 Formulations, Pack Sizes & Retail Prices Currency: Rs.
Dosage Form Reg. No Pack Size Trade Price (TP) Maximum Retail Price (MRP)
Tab 160/5/12.5 mg 076357 28 Rs.427.41 Rs.502.82
Tab 160/5/25 mg 076358 28 Rs.424.39 Rs.499.28
Tab 160/10/12.5 mg 076362 28 Rs.454.34 Rs.534.52
Tab 160/10/25 mg 076359 28 Rs.454.34 Rs.534.52 Tab 320/10/25

📋 Indications & Clinical Dosage

*Hypertension not adequately controlled by valsartan and amlodipine:* Adults: 1 tab daily using the strength as clinically appropriate. Children: Not recommended.

⛔ Contraindications

Biliary cirrhosis or cholestasis.

⚠️ Precautions & Warnings

Patients with activated renin-angiotensin system that are receiving angiotensin receptor blockers, hepatic impairment or biliary obstructive disorders, aortic or mitral stenosis or obstructive hypertrophic cardiomyopathy, hyperkalaemia.

🔄 Drug Interactions

K supplements, K-sparing diuretics, K-containing salt substitutes or other drugs that may increase K levels (heparin, etc.)

⚠️ Adverse Reactions / Side Effects

Renal impairment, cough, fatigue, GI disturbance, headache, syncope, hypersensitivity reactions, myalgia, neutropenia, pruritus, rash,serum sickness, thrombocytopenia, vasculitis, nasopharyngitis, flu, oedema (pitting, facial, peripheral), flushing, asthenia, hot flush.

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:
Contraindicated in pregnancy.
Lactation / Breastfeeding:
Not recommended.

📚 Official Regulatory & Clinical References

  • Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
  • World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
  • Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.

Related Medicines

Medicines related to this brand, grouped by relevance.

Same generic: AMLODIPINE, VALSARTAN AND HYDROCHLOROTHIAZIDE

ACOID
NEUTRO PHARMA
Rs.214.00
AMARUS
WINLET
Rs.157.50
AMODIP-V PLUS
MASS PHARMA
Rs.246.00
AMSART-H
MACTER
Rs.377.26
Rs.441.00
CO-AMSTAN
SCILIFE
Rs.475.67 559.72

More from PHARMEVO

ACTIFLOR
PHARMEVO
Rs.705.50
AGOVIZ
PHARMEVO
Rs.837.00
AIREEZ
PHARMEVO
Rs.374.00

Same category: ANGIOTENSIN-II ANTAGONISTS, COMBINATIONS

A2A
WILSONS
Rs.310.50
Rs.200.00
ADDRESS
SCOTMANN
Rs.600.00

⚡ Quick Actions

💬 Share via WhatsApp