CYCLOPHOSPHAMIDE

*Rheumatoid arthritis with severe systemic manifestations:* ORAL: Adult: 1-1.5 mg/kg daily. *Severe systemic rheumatoid arthritis, Other connective tissue diseases (especially with active vasculitis):* BY IV INJ: Adult: 0.5-1g every 2 weeks, then reduced to 0.5-1g, with prophylactic mesna, every mon...