📋 Indications & Clinical Dosage
*In combination with ribavirin (with or without peginterferon alfa) for the treatment of chronic hepatitis C infection of genotypes 1, 3, 4, 5, or 6 in patients with compensated liver disease, OR in combination with ribavirin for chronic hepatitis C infection of genotype 2 in patients with compensated liver disease OR in combination with daclatasvir for chronic hepatitis C infection of genotype 1, 3, or 4:*
Adults: 400 mg once daily with food. Continue for up to 24 week.
🔄 Drug Interactions
Telaprevir, boceprevir, other direct-acting HCV antivirals. Modafinil, potent P-gp inducers (e.g. rifamycins, carbamazepine, phenytoin, phenobarbital)
⚠️ Adverse Reactions / Side Effects
Agitation, alopecia, anaemia, anxiety, arthralgia, asthenia, blurred vision, chest pain, constipation, decreased appetite, depression, diarrhoea, dizziness, dry mouth, dyspnea, gastro-oesophageal reflux, abdominal discomfort, headache, influenza-like symptoms, insomnia, irritability, memory impairment, migraine, myalgia, nausea, neutropenia,rash, vomiting, weight loss