📋 Indications & Clinical Dosage
*Diarrhoea that is not associated with fever, bloody diarrhoea, blood or leucocytes in the stool, or 8 or more unformed stools in the previous 24 hours:*
Adult: 200 mg every 8 hours for 3 days.
*Reduction in recurrence of hepatic encephalopathy:*
Adult: 550 mg twice daily.
⛔ Contraindications
Intestinal obstruction, should not be used in patients with diarrhoea complicated by fever, rifamycin hypersensitivity
⚠️ Precautions & Warnings
Caution when used for hepatic encephalopathy in patients with severe hepatic impairment. If patients develop difficulty in breathing, swelling of face, lip, tongue, or throat discontinue.
⚠️ Adverse Reactions / Side Effects
Abdominal pain, depression, diarrhoea, dizziness, dyspnea, flatulence, headache, muscle spasm, nausea, pruritus, rash, vomiting, anorexia, antibiotic-associated colitis, anxiety, blood disorders, convulsions, dry mouth, dysuria, glycosuria, hyperkalaemia, hypoaesthesia, influenza-likesymptoms, memory impairment, paraesthesia, peripheral oedema, polymenorrhoea, polyuria, sleep disturbances, taste disturbances. Rare: Blood pressure changes, syncope