📋 Indications & Clinical Dosage
*Androgen deficiency, Male infertility associated with Hypogonadism:*
Adult: Initially 1 tab three or four times daily for several mth. Maintenance, 2-3 tab daily. Children: Not applicable.
⛔ Contraindications
Carcinoma of the male breast or prostate, hypercalcaemia, impaired liver function, pregnancy, lactation.
⚠️ Precautions & Warnings
Cardiac, hepatic or renal insufficiency, epilepsy, migraine, hypertension. Large and repeated doses in puberty may cause premature epiphyseal closure and stop linear growth. Hepatic adenocarcinoma may develop with prolonged use. In women high doses long term therapy pro-duces virilism including irreversible voice deepening.
🔄 Drug Interactions
In diabetic patients the metabolic effect of androgen may decrease blood glucose and insulin or hypoglycaemic agent requirements.
⚠️ Adverse Reactions / Side Effects
Female: Amenorrhoea and other menstrual irregularities. Male: Gynaecomastia, excessive frequency and duration of penile erections, inhibition of testicular function, testicular atrophy, impotence, priapism, Suppression of spermatogenesis