SAYDOZINE

*Symptomatic relief of allergy such as hay fever and Urticaria, Insomnia associated with urticaria andpruritus:* ORAL: Adult: 10-20 mg 2-3 times a day Children 2-4 yrs: 5 mg twice daily, alternatively 5-15 mg once daily at night; 5-9 yrs: 5-10 mg twice daily, alternatively 10-25 mg once daily at night; 10-17 yrs: 10-20 mg 2-3 times a day, alternatively 25 mg once daily at night, increased if necessary to 25 mg twice daily. BY DEEP IM INJ: Adult: 25-50 mg (max. per dose 100 mg); may be repeated in 2 hr. *Emergency treatment of anaphylactic reactions:* BY SLOW IV INJ: Adult: 25-50 mg, to be administered as a solution containing 2.5 mg/ml in water for injections; max. 100 mg per course; may be repeated in 2 hr. *Sedation (short-term use):* ORAL: Adult & Children above 10 yrs: 25-50 mg. Children 2-4 yrs: 15-20 mg; 5-9 yrs: 20-25 mg. BY DEEP IM INJ: Adult: 25-50 mg every 6 hr as needed. Children: 0.5-1 mg/kg/dose every 6 hr as needed (max 25mg/dose). *Nausea, Vomiting, Vertigo, Labyrinthine disorders, Motion sickness:* ORAL: Adult & Children above 10 yrs: 20-25 mg at bedtime on night before travel, repeat following morning if necessary Children 2-4 yrs: 5 mg at bedtime on night before travel, repeat following morning if necessary; 5-9 yrs: 10 mg at bedtime on night before travel, repeat following morning if necessary. BY IM OR IV INJ: Adult: 12.5-25 mg every 4-6 hr as needed. Children: 0.25-1 mg/kg 4-6 times/day as needed.

Administer IM into deep muscle mass. IV ad-ministration is not preferred route. Solution for injection may be diluted in 25-100 ml NS or D5W (max conc. of 25 mg/ ml) and infuse over 15-30 min at a rate of 25 mg/min.

Alcohol, CNS depressants, MAOls.

Headache, drowsiness, impaired reactions, dizziness, disorientation, photosensitivity, extra-pyramidal reactions, convulsions (high doses).