📋 Indications & Clinical Dosage
*Reversal of hypotension from spinal or epidural Anaesthesia:*
BY SLOW IV INJ: Adult: 3-6 mg every 3-4 minutes (max. per dose 9 mg), adjusted according to response; max.30 mg per course.
Children 1-12 yr: 500-750 mcg/kg or 17-25 mg/square meter every 3-4 min according to response, max 30 mg during episode; 12-18 yr: 3-7.5 mg, max 9 mg repeated every 3-4 minutes according to response, max 30 mg per course.
*Reversible airways obstruction:*
ORAL: Adult: 15-60 mg 3 times a day
Children above 4 yr: 10 mg three times daily.
*Neuropathic oedema:*
ORAL: Adult: 30-60 mg 3 times a day.
💊 Mode of Administration
Administer by SC, IM or slow IV route,IV injection of a solution containing ephedrine hydro-chloride 3 mg/ml
⛔ Contraindications
Coronary disease, hyperthyroidism, hypertension, prostatic hypertrophy, closed angle glaucoma, hyperexcitibility
⚠️ Precautions & Warnings
Diabetes, severe renal and hepatic impairment, cardiac disorder
🔄 Drug Interactions
MAOls, anaesthetics, TCADs.
⚠️ Adverse Reactions / Side Effects
GI distress, headache, nausea, anxiety, restlessness, insomnia, tremor, arrhythmia.
🤰 Pregnancy & Lactation Safety
Pregnancy Risk:
Caution advised
Lactation / Breastfeeding:
Caution advised
🧪 Compatibility & Storage Stability
Compatibility: ompatible with D5W, 010W, Ringer solution, LR, NS, 0.45% NS.