📋 Indications & Clinical Dosage
*Induction of anaesthesia:*
BY SLOW IV INJ: Adult & Children above 6 months: 150-300 mcg/kg (max. per dose 60 mg), to be administered over 30-60 seconds (60 seconds in patients in whom hypotension might be hazardous)
Elderly: 150-200 mcg/kg (max. per dose 60 mg), to be administered over 30-60 seconds (60 seconds in patients in whom hypotension might be hazardous)
⚠️ Precautions & Warnings
Acute circulatory failure (shock), acute porphyrias (avoid), adrenal insufficiency, cardiovascular disease, elderly, fixed cardiac output, hypovolaemia
⚠️ Adverse Reactions / Side Effects
Apnoea, hyperventilation, hypotension, nausea, rash, stridor, vomiting, arrhythmias, cough, hiccups, hypersalivation, hypertension, phlebitis, AV block, cardiac arrest, extraneous muscle movement, pain on injection, respiratory depression, seizures, shivering, Stevens-
Johnson syndrome