📋 Indications & Clinical Dosage
*Treatment of muscle spasm associated with acute painful musculoskeletal conditions:*
Adults: Initially 5 mg 3 times a day, increased to 10 mg 3 times/day if needed; dose not to be used longer than 3 weeks. Elderly: 5 mg 3 times a day; dose not to be used longer than 3 weeks. Children: Not recommended.
⛔ Contraindications
Do not use concomitantly or within 14days of MAO inhibitors, hyperthyroidism, congestive heart failure, arrhythmias, acute recovery phase of MI.
⚠️ Precautions & Warnings
Cyclobenzaprine shares the toxic potentials of the tricyclic antidepressants and the usual precautions of tricyclic antidepressant therapy should be observed, use with caution in patients with urinary hesitancy, angle-closure glaucoma, hepatic impairment, elderly
🔄 Drug Interactions
CYP1A2 inhibitors. TCAD, anticholinergics. CNS depressants, MAO inhibitors, tramadol
⚠️ Adverse Reactions / Side Effects
Agitation, anxiety, ataxia, cardiovascular depression, confusion, dizziness, drowsiness, dry mouth, euphoria, GI disturbances, hallucinations, headache, hyperhidrosis, hypotension, insomnia, myalgia, nightmares, rash, respiratory depression, sedation, seizure, tremor, urinary disturbances, visual disorders, abdominal pain, xerostomia.