📋 Indications & Clinical Dosage
*Benign gastric ulceration, Benign duodenal ulceration:*
Adults & Children above 15yrs: 2 gm twice daily in the morning and at bedtime, alternatively 1 g 4 times a day for 4-6 weeks, or in resistant cases up to 12 weeks, dose to be taken 1 hour before meals and at bedtime; max. 8 g per day.
*Chronic gastritis, Reflux oesophagitis:*
Adult: 2 g twice daily, dose to be taken on rising and at bedtime, alternatively 1 g 4 times a day for 4-6 weeks or in resistant cases up to 12 weeks, dose to be taken 1 hour before meals and at bedtime; max. 8 g per day.
*Prophylaxis of stress ulceration in child under intensive Care:*
Adults & Children above 15yrs: 1 g 6 times a day; max. 8 g per day.
*Prophylaxis of stress ulceration:*
Adult: 1 g 6 times a day; max. 8 g per day
Children below 15yrs: Not recommended.
⛔ Contraindications
Dialysis.
⚠️ Precautions & Warnings
Renal impairment. Patients under intensive care (reports of bezoar formation) caution is advised in seriously ill patients, especially those receiving concomitant enteric feeds or those with predisposing conditions such as delayed gastric emptying.
🔄 Drug Interactions
warfarin
⚠️ Adverse Reactions / Side Effects
Constipation, back pain, dizziness, drowsiness, dry mouth, headache, flatulence, gastric discomfort, indigestion, nausea, diarrhoea, rash. Rare: Bezoar formation and hepatic dysfunction
🤰 Pregnancy & Lactation Safety
Pregnancy Risk:
No evidence of harm
Lactation / Breastfeeding:
Caution advised