🩺 ANTINEOPLASTICS 🏷️ Tyrosine kinase inhibitor
📦 Formulations, Pack Sizes & Retail Prices Currency: Rs.
Dosage Form Reg. No Pack Size Trade Price (TP) Maximum Retail Price (MRP)
Tab 100 mg 30 Rs.244943.00 Rs.288168.24

📋 Indications & Clinical Dosage

*Anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer:* Adult: 100 mg daily, for dose adjustments consult product literature.

⛔ Contraindications

Congenital long QT syndrome

⚠️ Precautions & Warnings

Cardiac risk factors or conditions which may affect left ventricular ejection fraction; monitor ECG before starting treatment and monthly thereafter, worsening respiratory symptoms, indicative of interstitial lung disease or pneumonitis (including dyspnoea, cough, and fever, avoid in moderate to severe hepatic impairment; monitor for lipase and amylase elevations before starting treatment, and regularly thereafter as clinically indicated. monitor serum cholesterol and triglycerides before starting treatment, then at weeks 2, 4, and 8, and regularly thereafter, avoid in severe renal impairment.

🔄 Drug Interactions

CYP3A4 inhibitors

⚠️ Adverse Reactions / Side Effects

Anaemia, anxiety, arthralgia, asthenia, behaviour abnormal, cognitive disorder, concentration impaired, confusion, constipation, delirium, dementia, depression, diarrhoea, dyslipidaemia, gait abnormal, hallucinations, headache, inflammation, learning disability, memory loss, mental impairment, mood altered, muscle weakness, myalgia, nausea, nerve disorders, neurotoxicity, oedema, pain, peroneal nerve palsy, respiratory disorders, speech impairment, vision disorders, vitreous floater, weight increased. Rare: Atrioventricular block.

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:
Avoid unless essential
Lactation / Breastfeeding:
Contraindicated. Discontinue breast-feeding

🔄 Alternative Brands

Other brands containing LORLATINIB

No other brands registered under this generic ingredient in the directory.

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