📋 Indications & Clinical Dosage
*Obesity with body mass index(BMI) 30 kg/m2 and greater, or BMI 28 kg/m2 and greater with other risk factors:*
Adults: 120 mg before, during or up to one hr after each main meal. Continue treatment after 12 wk if 5% of initial body weight is reduced. If a meal is missed or contains no fat, the dose of orlistat should be omitted. Advise diet rich in fruit and vegetables containing approx 30% calories from fat. Consider a multivitamin supplement
Children: Not recommended.
🔄 Drug Interactions
Acarbose, anticoagulants, amiodarone, fat-soluble vitamins, cyclosporin.
⚠️ Adverse Reactions / Side Effects
Abdominal distension, abdominal pain, anxiety, faecal incontinence, faecal urgency, flatulence, gingival disorders, headache, hypoglycaemia, liquid stools, malaise, menstrual disturbances, oily leakage from rectum, oily stools, respiratory infections, tooth disorders, urinary tract infection, bullous eruptions, cholelithiasis, diverticulitis, hepatitis, hypothyroidism, oxalate nephropathy, rectal bleeding.