📋 Indications & Clinical Dosage
*Peripheral vascular disorders, varicose vein, cerebro-vascular disorders including strokes, transient ischaemic attacks, sequela of head Injury:*
See literature for specific dosage
💊 Mode of Administration
IV Administer undiluted using a fine-gauge (26 or 30 gauge) needle, insert needle tangentially into af-fected vein and inject solution slowly. Apply only gentle pressure during inj to prevent vein rupture. If repeated treatments are needed, separate by 1- 2 weeks. Following inj, apply compression via stocking or bandage to reduce risk of deep vein thrombosis.
⛔ Contraindications
Cardiac disorder, hypertension, elderly, pregnancy
⚠️ Precautions & Warnings
History of allergy, risk of anaphylaxis (monitoring required), renal and hepatic impairment.
⚠️ Adverse Reactions / Side Effects
Pulmonary embolism, paraesthesia, dizziness, anaphylactic shock, syncope, cardiac arrest, dyspnea, vaso-vagal attack, asthma, deep vein thrombosis
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.