👨‍⚕️ Clinically Reviewed by: PakistaniBano Medical Editorial Board (Pharm.D Panel)
📅 Reviewed: November 2026 • 🔍 Authority: DRAP / WHO ATC
📦 Formulations, Pack Sizes & Retail Prices Currency: Rs.
Dosage Form Reg. No Pack Size Trade Price (TP) Maximum Retail Price (MRP)
Sachet 10mg — 16 Rs.366 Rs.430.00
Sachet 30mg — 10 Rs.374 Rs.440.00
Cap 100mg — 10 Rs.468 Rs.550.00

📋 Indications & Clinical Dosage

*Acute diarrhoea:* Adults: 3 sachets daily in 2-3 divided doses, mixed in a glass of water. In acute diarrhoea the initial dosage can be doubled. Children below 1 yr: 1 sachet daily; 1-2 yr:1-2 sachets daily; above 2 yr:2to 3 sachets daily in 2-3 divided dose.

⛔ Contraindications

Patients with hereditary problems of fructose intolerance, glucose-galactose malabsorption syndrome or saccharase-isomaltase deficiency

⚠️ Precautions & Warnings

patients with hepatic or renal impairment

⚠️ Adverse Reactions / Side Effects

Aggravation of constipation, rash, erythema, oedema, pruritus

📚 Official Regulatory & Clinical References

  • Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
  • World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
  • Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.

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