SAMCOL (COLCHICINE) Price

Dosage Form	Reg. No	Pack Size	Trade Price (TP)	Maximum Retail Price (MRP)
Tab 50 mg	—	10	Rs.286.00	Rs.337.00

📋 Indications & Clinical Dosage

*Acute gout:* Adult: 500 mcg 2-4 times a day until symptoms relieved, max. 6mg per course, do not repeat course within 3 days. *Short-term prophylaxis during initial therapy with allopurinol and uricosuric drugs:* Adult: 500 mcg twice daily. *Prophylaxis of familial Mediterranean fever (recurrent polyserositis):* Adult: 0.5-2 mg once daily. Children: Not recommended.

⛔ Contraindications

Blood disorder

⚠️ Precautions & Warnings

GI disease, cardiac disease, hepatic impairment, renal impairment, elderly

🔄 Drug Interactions

Cyclosporin.

⚠️ Adverse Reactions / Side Effects

Nausea, vomiting, and abdominal pain, excessive doses may also cause profuse diarrhoea, GI haemorrhage, rashes, renal and hepatic damage. Rare: peripheral neuritis, myopathy, alopecia, inhibition of spermatogenesis, and with prolonged treatment blood disorders.

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:

Contraindicated in pregnancy

Lactation / Breastfeeding:

Caution advised

📚 Official Regulatory & Clinical References

Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.