📋 Indications & Clinical Dosage
*Upper Respiratory Infection (Streptococcal):*
Adults & Children 12 yrs: 125-500 mg every 6 hr for 10 days.
*Lower Respiratory Infection (Pneumococcal):*
Adults & Children 12yrs: 250-500 mg every 6 hr until a febrile for 2 days.
*Skin Infection:*
Adults & Children above 12 yrs: 250-500 mg every 6-8 hr.
*Fusospirochetosis (Oropharynx):*
Adults & Children above12 yrs: 250-500 mg every 6-8.hr.
*Pneumococcal:*
Adults & Children above 12 yrs: 250-500 mg every 6 hr until afebrile for 2 days.
⚠️ Precautions & Warnings
Avoid small ineffective doses of penicillin as resistant organisms are more likely to emerge, therapy must be sufficient to eliminate the streptococcal organism (a minimum of ten days), otherwise the sequela of streptococcal disease (endocarditis, rheumatic fever) may occur. Serious fatal immediate hypersensitivity (anaphylactoid) reactions have been reported. Do not inject par-enteral solutions into or near an artery or nerve
⚠️ Adverse Reactions / Side Effects
GI disturbances, anaemias, anaphylaxis, glossitis, stomatitis, gastritis, sore throat, dry mouth, furry tongue, Hemorrhagic manifestation, interstitial nephritis (e.g oliguria, hematuria), nephrotoxicity, accumulation of sodium from injection can occur in renal failure. High doses may cause neurotoxicity, including cerebral irritation, convulsions, or coma.