📋 Indications & Clinical Dosage
*Intestinal inflammatory disorders, ulcerative colitis, Crohns disease:*
Adults: 6 tabs daily in divided doses; maintenance, 3-6 daily in divided doses.
Children: Not recommended.
⛔ Contraindications
Hypersensitivity to salicylates, blood dyscrasias (blood count required)
⚠️ Precautions & Warnings
Renal impairment and raised blood urea or proteinuria, pregnancy, elderly.
🔄 Drug Interactions
Lactulose. Products that decrease stool pH.
⚠️ Adverse Reactions / Side Effects
Hepatitis, bronchospasm, nephrotic syndrome, blood dyscrasias, myocarditis, pericarditis, GI disturbances, headache.
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.