📋 Indications & Clinical Dosage
*Heartburn, hiatus hernia, reflux oesophagitis, dyspepsia due to reflux:*
Adults: 10-20 ml after meals and at night.
Children: Half adult dose.
⚠️ Precautions & Warnings
Renal impairment, patients on low phosphate diet, hepatic impairment. Antacids may damage enteric coatings designed to prevent dissolution in the stomach.
🔄 Drug Interactions
May alter absorption of tetracyclines, INH, warfarin Fe salts, H2-receptor antagonists, quinidine.
⚠️ Adverse Reactions / Side Effects
Vomiting, nausea, diarrhoea, constipation, intestinal obstruction.
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.