📋 Indications & Clinical Dosage
*Relief of pain in rheumatic condition and musculoskeletal disorders, Treatment in knee or hand osteoarthritis (adjunct):*
Adult: Apply 2-4 times a day for up to 7 days, ketoprofen 2.5% gel to be administered; max. 15 g per day. Treatment should not exceed 10 days.
Children below 12 yrs: Not recommended.
⛔ Contraindications
Asthma, aspirin/anti-inflammatory induced allergy, hypersensitivity
⚠️ Precautions & Warnings
Avoid contact with eyes and lips, avoid contact with inflamed or broken skin, avoid contact with mucous membranes, not for use with occlusive dressings, topical application of large amounts can result in systemic effects, including hypersensitivity and asthma (renal disease has also been reported), avoid in pregnancy and lactation
⚠️ Adverse Reactions / Side Effects
Local erythema, pruritus, dermatitis, photo-sensitivity, skin rash.
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.