📋 Indications & Clinical Dosage
*Treatment of cerebral insufficiency, dementia, dizziness, impaired memory, tinnitus, vertigo:*
ORAL: Adults: 1 tab (1.5 mg) or 30 drops 2 to 3 times daily preferably before meals or 2 to 3 tab or 60-90 drops or 1 tab of 4.5 mg once daily before breakfast for 3 mth or more, Children: Not recommended.
BY IM INJ: Adults: 1 amp (1 ml) twice daily intramuscularly for one week, followed by therapy with tab.
*Acute cerebrovascular diseases, migraine and vascular headaches, cerebrovascular accident (stroke):*
BY IV DRIP: Adults: Day 1 to day 3, 9-10 ml in 1000 ml of physiological saline given as an IV drip, every 24 hr. Day 4 to day 10, 3 ml IM every 12 hr. Followed by oral therapy with tab/soln.
Children: Not recommended.
💊 Mode of Administration
Doses of 300 mcg can be given IM, SC or by IV infusion.
⚠️ Precautions & Warnings
Severe bradycardia, pregnancy, monitors blood pressure during treatment. Reduce dose in hepatic and renal impairment
⚠️ Adverse Reactions / Side Effects
GI upset, nausea, flushes, rash, nasal congestion, crams, headache, dizziness
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.