🩺 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS 🏷️ Corticosteroid/B2-agonist 💊 Anti-asthmatic
👨‍⚕️ Clinically Reviewed by: PakistaniBano Medical Editorial Board (Pharm.D Panel)
📅 Reviewed: November 2026 • 🔍 Authority: DRAP / WHO ATC
📦 Formulations, Pack Sizes & Retail Prices Currency: Rs.
Dosage Form Reg. No Pack Size Trade Price (TP) Maximum Retail Price (MRP)
DPI Cap 100/50 mcg — 30 Rs.510.00 Rs.600.00
DPI Cap 250/50 mcg — 30 Rs.535.50 Rs.630.00
DPI Cap 500/50 mcg — 30 Rs.561.00 Rs.660.00

📋 Indications & Clinical Dosage

*Treatment of asthma, treatment of Chronic Obstructive Pulmonary Disease:* Adults: 1 inhalations twice daily at lowest effective inhaled corticosteroid dose.

⚠️ Precautions & Warnings

Severe cardiovascular disorders, pulmonary tuberculosis, diabetes, hypokalaemia, thyrotoxicosis, pregnancy, lactation. Prolonged treatment with high doses increases risk of adrenal suppression and systemic effects; monitor adrenal function. Monitor height of children on prolonged therapy. Consider additional steroid therapy during stress or surgery. Withdraw gradually.

🔄 Drug Interactions

Beta-blockers.

⚠️ Adverse Reactions / Side Effects

Headache, anxiety, depression, dryness, epistaxis, hyperactivity, hypersensitivity reactions, nasal irritation, nasal ulceration, sleep disturbances, smell disturbances, taste disturbances, oropharyngeal irritation. Rare: Paradoxical bronchospasm; discontinue immediately.

📚 Official Regulatory & Clinical References

  • Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
  • World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
  • Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.

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