🩺 ANTIMALARIALS 🏷️ 4-Methanolquinolone/Diaminopyrimidine/ Sulphonamide
👨‍⚕️ Clinically Reviewed by: PakistaniBano Medical Editorial Board (Pharm.D Panel)
📅 Reviewed: November 2026 • 🔍 Authority: DRAP / WHO ATC
📦 Formulations, Pack Sizes & Retail Prices Currency: Rs.
Dosage Form Reg. No Pack Size Trade Price (TP) Maximum Retail Price (MRP)
Tab — 30 Rs.994.50 Rs.1170.00

📋 Indications & Clinical Dosage

*Therapy of plasmodium falciparum malaria resistant to other antimalarial agents:* Adults: Non-immune patients: Single dose of 3 tab. Semi-immune patients: 60 kg or less body-weight: AZ Single dose of 2 tab, more than 60 kgbody-weight: single dose of 3 tablets. Children: Single dose of 1/2 to 2 tabs according to age.

⛔ Contraindications

Sulphonamide hypersensitivity.

⚠️ Precautions & Warnings

Impaired renal or hepatic function, porphyria, psoriasis,severe gastrointestinal, neurological or blood disorders, infants up to two months.

🔄 Drug Interactions

Folate inhibitors.

⚠️ Adverse Reactions / Side Effects

Abdominal cramp, blood dyscrasias, GI distress, nausea, vomiting, weakness, diarrhoea, muscular cramp, malaise, irregular heartbeat, skin-pigmentation, hair loss, tinnitus, lumpus erythematosus, corneal opacities, retinal damage, blood disorders,headache, skin reactions and liver cell damage.

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:
: Contraindicated
Lactation / Breastfeeding:
Contraindicated

📚 Official Regulatory & Clinical References

  • Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
  • World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
  • Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.

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