📋 Indications & Clinical Dosage
*Passive immunization in suspected cases of diphtheria:*
BY IV INF: Adult: Dose should be given without waiting for bacteriological confirmation. Consult product literature for prescribing details.
⚠️ Precautions & Warnings
Diphtheria antitoxin is derived from horse serum and reactions are common; tests for hypersensitivity should be carried out before use, Hypersensitivity is common after administration; resuscitation facilities should be available. Diphtheria antitoxin is no longer used for prophylaxis because of the risk of hypersensitivity; unimmunized contacts should be promptly investigated and given antibacterial prophylaxis and vaccine.
⚠️ Adverse Reactions / Side Effects
Hypersensitivity reactions
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.