📋 Indications & Clinical Dosage
*Adjunct therapy in chronic debilitating diseases, glucocorticoid therapy, radiotherapy, major surgery and trauma:*
Adults: 25-50 mg every 3 wk.
*Anaemia of chronic renal failure:*
MALE: 200 mg every wk; FEMALE: 100 mg every wk.
*Aplastic anaemia:*
MALE & FEMALE:50-150 mg every wk
*Anaemia due to cytotoxic therapy:*
MALE & FEMALE:200 mg every wk
This treatment should be continued throughout the cytotoxic therapy and recovery period until the blood count returns to normal.
⛔ Contraindications
Pregnancy, prostatic carcinoma or mammary carcinoma in males, development of signs of virilization.
⚠️ Precautions & Warnings
Anabolic steroids may occasionally induce salt and fluid retention.To be administered by deep IM injection.
🔄 Drug Interactions
Anticoagulants, liver enzyme inducers, Heparin.
⚠️ Adverse Reactions / Side Effects
Over dose or prolong treatment may cause amenorrhoea and inhibition of spermatogenesis, premature epiphyseal closure, water and salt retention, virilization in sensitive women.
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.