📋 Indications & Clinical Dosage
*Amoebiasis, trichomoniasis:*
Adults: 2 tab 3 times daily for 5-10 days.
Children below 4 yrs: 5 ml suspension thrice daily; 4-12 yr: 10 ml suspension thrice daily.
⛔ Contraindications
: Hepatic damage, pre-existing optic neuropathy
⚠️ Precautions & Warnings
CNS disorders, hepatic encephalopathy
🔄 Drug Interactions
Alcohol, anticoagulants, phenobarbitone, lithium, anticoagulants, phenobarbitone, alcohol,
⚠️ Adverse Reactions / Side Effects
CNS disturbances, GI disturbance, furred tongue, leucopenia, angioedema, dark urine, neuropathy and epileptic form seizures on long term therapy, urticaria, unpleasant taste
🤰 Pregnancy & Lactation Safety
Pregnancy Risk:
Contraindicated
Lactation / Breastfeeding:
Contraindicated
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.