CYNOTONE (VITAMIN B12) Price

Dosage Form	Reg. No	Pack Size	Trade Price (TP)	Maximum Retail Price (MRP)
Inj 1000 mcg	017772	100 Ampx1 ml	Rs.221.00	Rs.260.00
Inj 1000 mcg	017772	25 Ampx1 ml	Rs.83.98	Rs.98.80

📋 Indications & Clinical Dosage

*Megaloblastic anaemia, megaloblastosis caused by prolonged nitrous oxide anaesthesia, congenital transcobalamin II deficiency, post gastrectomy or total ilea resection vitamin B12 deficiency:* INJ: Adults: By IM or deep SC, initially 1000 mcg repeated 10 times at intervals of 2-3 days, maintenance 1000 mcg every mth. ORAL: Adults: 50-150 mcg daily taken between meals. Children: 50-105 mcg daily in 1-3 divided doses.

⚠️ Adverse Reactions / Side Effects

Urticaria, angioneurotic edema, jaundice, peptic ulceration, pulmonary edema, cyanosis, headache, GI upset, pruritus, breathing difficulty, allergic reactions

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:

Caution advised, risk cannot be ruled out.

Lactation / Breastfeeding:

Caution advised or effect undetermined.

📚 Official Regulatory & Clinical References

Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.