📋 Indications & Clinical Dosage
*Anorexia, mood elevation in the elderly, prophylactic treatment of migraine:*
Children: 2-6 yr, 5-10 ml of daily;
6-12 yr, 10-20 ml daily in 2 or 3 divided doses, maintenance doses, 5 ml/kg body-wt daily.
Adults: Starting with 10 ml per day, may be increased to 10 ml 3 times a day.
⚠️ Precautions & Warnings
Patients with narrow angle glaucoma or urinary retention (dueto slight anticholinergic effect of pizotifen), pregnancy and lactation.
🔄 Drug Interactions
Sedatives, hypnotics, antihistamines, alcohol.
⚠️ Adverse Reactions / Side Effects
Sedation, dizziness, dry mouth, constipation.
📚 Official Regulatory & Clinical References
- Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
- World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
- Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.