👨‍⚕️ Clinically Reviewed by: PakistaniBano Medical Editorial Board (Pharm.D Panel)
📅 Reviewed: November 2026 • 🔍 Authority: DRAP / WHO ATC
📦 Formulations, Pack Sizes & Retail Prices Currency: Rs.
Dosage Form Reg. No Pack Size Trade Price (TP) Maximum Retail Price (MRP)
Eye Drop 1 % — 5 ml — Rs.81.60.96.00
Eye Drop 2 % 026377 5 ml Rs.130.47 Rs.153.50

📋 Indications & Clinical Dosage

*Ocular hypertension, chronic open angle glau-coma and some secondary glaucoma:* Adults: 1 drop of 1% in the affected eye two times daily. If response inadequate use 1 drop of 2% in the affected eye two times daily.

⛔ Contraindications

Cardiac insufficiency, asthma or chronic obstructive pulmonary disease, soft contact lenses.

⚠️ Precautions & Warnings

Sinus bradycardia, 2nd or 3rd degree AV block cardiogenic shock, right ventricular insufficiency due to pulmonary hypertension or congestive heart failure, diabetes.

🔄 Drug Interactions

Systemic beta-blockers.

⚠️ Adverse Reactions / Side Effects

Ocular irritation, itching, burning, pain, blurred vision, photophobia, xerosis, conjunctival dis-charge, corneal disorders, hyperaemia, vertigo, diffuse superficial keratitis, bradycardia, rash, bronchospasm, dyspnoea headache, lassitude.

🤰 Pregnancy & Lactation Safety

Pregnancy Risk:
Caution advised
Lactation / Breastfeeding:
Not recommended.

📚 Official Regulatory & Clinical References

  • Drug Regulatory Authority of Pakistan (DRAP): Drug Registration, S.R.O. Price Gazettes & National Essential Medicines List (NEML).
  • World Health Organization (WHO): Collaborating Centre for Drug Statistics Methodology (ATC/DDD Index).
  • Formulary Standards: British National Formulary (BNF) & Pakistan National Formulary (PNF) guidelines.

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